The agreement is signed but something needs to change

If the agreement has been fully signed it goes into a status of complete. If you need to change the agreement after it is completed, you need to create a new agreement to supersede it. You can use the ‘Renewal button to create a new agreement, that you can edit that is based off your signed agreement that you can send out for resigning.

There are more details about how you can manage agreements in 2Shakes by understanding the status and versioning here.